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Tennessee Medicine E-Journal

Abstract

EBV-positive diffuse large cell lymphoma (DLBCL) of the elderly is a specific and a very aggressive form of clonal B-cell proliferation which generally observed over 50 years of age and without any known previous lymphoma or immunodeficiency. Rarely, it may be observed in younger individuals. Our case was a 24-year-old male. Histopathologic examination revealed atypical pleomorphic bizarre cells which were positive for CD45, CD20, CD79a immunohistochemically and positive for ın situ hybridization(ISH) for “Epstein-Barr virus-encoded mRNA (EBER)”. The case is reported with diagnosis and discriminative diagnosis.

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