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Tennessee Medicine E-Journal

Abstract

B-cell lymphoma, Unclassifiable, with features intermediate between diffuse large B-cell lymphoma and classical Hodgkin lymphoma, is usually discussed primarily as a mediastinal tumour. Authors have acknowledged that non-mediastinal cases can occur, but their features are not described in detail. Studies have shown some clinical (age) and genetic differences between mediastinal and non-mediastinal cases, but survival is similar. Recently, it was proposed that the name not change, but that two subtypes be distinguished as mediastinal and non mediastinal. Here, we report 3 nodal and 1 extranodal involvement cases of unclassifiable B-cell lymphoma with features intermediate between diffuse large B-cell lymphoma and classical Hodgkin lymphoma with no evidence of mediastinal disease.

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