Zika virus infection can cause microcephaly (<3 percentile head circumference) and other severe fetal brain defects. The Tennessee Department of Health (TDH) estimates birth defects incidence based on retrospective analyses of Hospital Discharge, Birth and Death Statistical Data Systems. This surveillance approach prevented TDH from detecting increases in microcephaly incidence associated with prenatal Zika virus infection.
Hartel, Marie Bottomley; Miller, Angela M.; McDonald, Morgan F.; and Warren, Michael D.
"Design and Implementation of a Real-Time Microcephaly Surveillance System,"
Tennessee Medicine E-Journal: Vol. 2
, Article 10.
Available at: http://ejournal.tnmed.org/home/vol2/iss3/10