Tennessee Medicine E-Journal


Objective: To determine the condition of sixteen of my myasthenia gravis patients treated with steroids for up to fifty years and determine the effect of long-term steroids if the dosage is properly adjusted.

Methods: Follow-up of sixteen patients treated for up to fifty years with ACTH or prednisone.

Results: Of the sixteen patients one patient was treated for thirty-four years, two patients for forty-five years and one for fifty years. Eight patients who had been treated four to forty-four years were deceased. Four patients were lost to follow-up.

Conclusion: Long-term, maintenance corticosteroid therapy is effective and safe if properly used for many years. The follow-up also shows that long-term steroids can be used for treatment of chronic diseases if the dosage is properly adjusted.